Measurement of serum GH and cortisol concentrations should routinely be included in the so-called “critical sample” obtained at the time of spontaneous hypoglycemia. Hypoglycemia due to deficiency of GH and/or cortisol most commonly occurs in neonates and children less than 5 years of age, but may also occur in older children and adults when food intake is limited e.g., when an illness results in anorexia and/or vomiting or when the patient is fasted prior to undergoing a procedure.ĭeficiency of GH and/or cortisol should always be considered in the differential diagnosis of non-hyperinsulinemic hypoglycemia. Glucagon, epinephrine, cortisol and growth hormone (GH) raise plasma glucose concentration and are referred to as glucose counterregulatory hormones. OVERVIEW: What every practitioner needs to know Are you sure your patient has counter-regulatory hormone deficiency? What are the typical findings for this disease?
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